
Nail polish remover is a common household product that contains acetone, a colorless solvent that can dissolve or break down other substances. While it is recognized as safe by the FDA, acetone has been linked to certain health risks, including irritation to the eyes, nose, throat, skin, and lungs. Inhalation of acetone fumes can lead to severe health issues, and in some cases, it is used intentionally to achieve a high. There have been concerns about the use of acetone-based nail polish removers in the illegal manufacture of drugs, particularly methamphetamine, leading to increased restrictions on the purchase of these products. Additionally, poppers, which are marketed as nail polish removers, contain nitrites and are ingested or inhaled for recreational purposes, posing serious health risks, including death.
| Characteristics | Values |
|---|---|
| Used for making drugs | Yes, acetone nail polish remover is used for making methamphetamine |
| Used for inhaling | Yes, some people inhale acetone-based nail polish remover to get high |
| Risks | Irritation, poisoning, damage to kidneys, liver, brain, and nervous system |
| ID required for purchase | Yes, some stores ask for a valid ID to purchase nail polish remover |
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What You'll Learn

Nail polish remover can be used to make methamphetamine
While nail polish remover is typically used to remove nail polish, it has also been used for illicit purposes, such as the production of methamphetamine. The key ingredient in nail polish remover that enables this is acetone. Acetone is a ubiquitous ingredient in many household products, including glue solvents, air fresheners, adhesives, nail polish, and paint.
Acetone is a well-known ingredient in the illegal manufacture of methamphetamine, commonly known as meth. As a result, some retailers, such as CVS stores in New England, have implemented restrictions on the sale of acetone-containing products, including nail polish remover. These restrictions include requiring customers to present a valid ID and imposing limits on the number of bottles that can be purchased.
The decision by CVS to restrict the sale of nail polish remover is not due to any specific regulation by the federal government or the Drug Enforcement Administration (DEA). Rather, it is a proactive measure taken by the company to curb the potential use of acetone in meth production. According to a CVS statement:
> "Because acetone is an ingredient used in the illegal manufacture of methamphetamine, we recently implemented a policy that a valid ID must be presented to purchase acetone-containing products such as nail polish remover. Our policy also limits the sale of these products in conjunction with other methamphetamine precursors and is based on various regulations requiring retailers to record sales of acetone."
While acetone is indeed used in the production of meth, it is important to note that it is not as tightly regulated as other key ingredients, such as pseudoephedrine. The DEA has not placed any specific restrictions on the over-the-counter sales of acetone. However, the presence of acetone in nail polish remover has led to its inclusion in efforts to prevent the diversion of common products for illicit drug manufacturing.
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Nail polish remover is ingested or inhaled to get high
Acetone is a colorless solvent that can be found in products such as nail polish and paint remover. It is also a natural byproduct of the breakdown of fat in the human body. While the Food and Drug Administration (FDA) classifies acetone as Generally Recognized as Safe, it does have some risks. For example, acetone liquid and vapors catch fire easily, and inhaling acetone fumes can irritate the eyes, nose, throat, or lungs. Severe exposure to acetone vapor may cause damage to the nervous system, confusion, or unconsciousness. Consuming large amounts of acetone may lead to acetone poisoning.
Nail polish remover can be ingested or inhaled to get high. This is because it contains acetone and alcohol. However, this is very dangerous as the chemicals in nail polish remover can seriously damage the kidneys, liver, brain, and nervous system.
There is limited evidence to suggest that acetone alone has any abuse liability. However, it has been shown that adolescent animals express a preference for an environment paired with toluene vapors, which is a solvent that is also present in nail polish remover.
In addition to the health risks associated with ingesting or inhaling nail polish remover, it is important to note that the products marketed as nail polish removers, known as "poppers," may contain nitrites. These products are often sold in small bottles resembling energy shots and are intended for recreational use or to enhance sexual experiences. The FDA advises against purchasing or using these products as they can result in serious adverse health effects, including death.
Overall, while it is possible to get high by ingesting or inhaling nail polish remover, it is extremely dangerous and can lead to serious health problems and even death.
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Acetone in nail polish remover can cause nervous system damage
Acetone is a colourless solvent that can be found in products such as nail polish and paint remover. It is also a natural byproduct of the breakdown of fat in the human body. While the Food and Drug Administration (FDA) classifies acetone as Generally Recognized as Safe, it does have certain risks. Inhaling acetone can irritate the eyes, nose, throat, or lungs, and can even cause severe nervous system damage, confusion, or unconsciousness.
Acetone is a ubiquitous ingredient in many household products, such as glue solvents, air fresheners, adhesives, nail polish, and paint. It is also present in tobacco smoke, vehicle exhaust, and landfills. Due to its availability, some people may inhale acetone-based nail polish remover to achieve a "high". This is extremely dangerous, as the chemicals in nail polish remover can seriously damage the kidneys, liver, brain, and nervous system.
The effects of acetone on the nervous system have been studied in animals, with varying results. Some research has shown that adolescent rats exposed to acetone vapors developed a preference for the substance, indicating the potential for abuse. However, other studies have suggested that acetone is a much less potent central nervous system (CNS) depressant than other solvents, such as toluene.
Despite the mixed findings in animal studies, there is evidence that solvent abuse, including the inhalation of acetone, is a significant health problem among adolescents in the US and worldwide. The potential for acetone abuse and its serious health risks have led to measures such as ID requirements and purchase limits for acetone-containing products like nail polish remover.
Overall, while acetone in nail polish remover may have legitimate uses, its potential for nervous system damage and other health risks cannot be overlooked. It is important to use these products with caution and to seek alternative, non-toxic options whenever possible.
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Nitrite poppers marketed as nail polish removers can cause death
Nitrite poppers, commonly referred to as "poppers", are often marketed as nail polish removers and sold online or at adult novelty stores. They are packaged in small bottles ranging from 10 to 40 mL, appearing similar to energy shots. Brand names include Jungle Juice, Extreme Formula, Hardware, Quicksilver, Super Rush, Super Rush Nail Polish Remover, and Premium Ironhorse, among others.
Poppers are a group of chemicals that people inhale to get high. They are typically made with amyl nitrite or similar substances, such as butyl nitrite, isobutyl nitrite, isopropyl nitrite, and cyclohexyl nitrite. These chemicals are similar to prescription medications used to relieve chest pain and dilate blood vessels. When inhaled, they can cause a feeling of euphoria or muscle relaxation, often enhancing sexual experiences.
However, the FDA strongly advises against the purchase or use of nitrite poppers due to their serious adverse health effects, including severe injury and death. These chemicals can be caustic and damage the skin or other tissues they come into contact with. Ingesting or inhaling poppers can cause difficulty breathing, extreme drops in blood pressure, decreased blood oxygen levels, seizures, heart arrhythmia, coma, and death.
While it is not illegal to sell the chemicals in poppers, they are usually marketed for other purposes, such as nail polish removers or cleaning products. Poppers have been popular as party drugs, especially in the gay and queer community, dating back to the 1970s. Although not addictive, they can lead to serious health problems or death, and users are advised to stop immediately and discard any unused product.
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Nail polish remover ingredients may cause reproductive harm
While nail polish remover is not a drug in itself, its ingredients can be used to make illegal substances. Acetone, a common ingredient in nail polish removers, is used in the manufacture of methamphetamine. As a result, some stores have started to ask for identification when selling nail polish remover and limit the number of bottles that can be purchased.
Nail polish remover ingredients may also cause reproductive harm. Isopropyl acetone, methyl ethyl ketone, and n-methyl-pyrrolidone are commonly used as solvents in nail polish removers. These chemicals have been linked to reproductive harm and organ toxicity. Studies have shown that exposure to these chemicals can cause respiratory and eye irritation, headaches, and nausea. N-Methyl-Pyrrolidone (NMP) has been identified as a reproductive toxin, with studies on pregnant rats showing an increased incidence of maternal toxicity and a higher likelihood of internal and external malformations in the offspring. Due to these concerns, the European Union has prohibited the use of N-Methyl-Pyrrolidone in cosmetics.
In addition to the potential harm caused by nail polish remover ingredients, the removal process of gel polish can also be destructive to nails. Soaking nails in acetone and aggressive buffing, scraping, or peeling of polish can injure the nail plate and lead to severe brittleness and dryness.
To address these concerns, consumers can choose nail polish removers without harmful chemicals. Protective measures, such as wearing nitrile gloves and ensuring proper ventilation, are also recommended for nail salon workers and owners.
It is worth noting that the potential harm caused by nail polish and its removers is not limited to reproductive health. The chemicals found in these products can have various adverse effects on the body, including skin and eye irritation, respiratory issues, and even organ damage. Additionally, the lack of ingredient labels on nail polish products makes it challenging for consumers to make informed decisions about the potential risks associated with their use.
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Frequently asked questions
Yes, acetone nail polish remover is an ingredient used in the illegal manufacture of methamphetamine.
Acetone is a colorless solvent that can break down or dissolve other materials.
The drug enforcement administration has classified acetone as a List I chemical, meaning it can be easily diverted for illicit purposes. Additionally, inhaling or ingesting acetone can irritate the eyes, nose, throat, or skin, and cause severe damage to the nervous system, confusion, or unconsciousness.
Yes, nail polish remover can contain other chemicals such as isopropyl acetone, methyl ethyl ketone, and n-methyl-pyrrolidone, which may cause reproductive harm and organ toxicity.
Yes, other solvents such as toluene, trichloroethane, ethanol, barbiturates, and benzodiazepines are known to be used in drug manufacturing. However, it is important to note that solvent abuse can lead to serious health problems and even death.











































