
Loceryl Nail Lacquer is a prescription-only medication used to treat fungal nail infections. It contains the active ingredient amorolfine, an antifungal that kills a wide variety of fungi and yeast. The treatment involves filing down the infected nail, cleaning the nail surface, and applying the lacquer once or twice a week. It is important to continue the treatment until the infection has cleared and healthy nails have grown back, which can take up to six months for fingernails and nine to twelve months for toenails.
| Characteristics | Values |
|---|---|
| Active ingredient | Amorolfine |
| Type of medicine | Antifungal |
| Application frequency | Once a week |
| Application technique | Applied like nail polish |
| Application duration | 6 months for finger nails, 9-12 months for toe nails |
| Application area | Affected finger or toe nails |
| Application instructions | File the nail, clean the nail, apply the lacquer, let it dry |
| Side effects | Blisters on the skin, nail damage and discolouration, skin irritation, rash, redness |
| Precautions | Avoid contact with eyes, ears, nose, mouth, flammable substances |
| Precautions for use | Do not use during pregnancy or breastfeeding, do not use artificial nails, do not share nail filer |
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What You'll Learn

Loceryl Nail Gel is an antifungal medication
Loceryl is applied directly to the affected nails once or twice a week, as directed by a doctor. Before application, it is crucial to prepare the nails properly. This involves filing down the infected areas of the nail, including the nail surface, using a nail file. The nail surface should then be cleaned with a swab or cleaning wipe to remove any grease or surface germs, ensuring a more porous surface for better lacquer adhesion.
After preparation, the Loceryl nail lacquer is applied evenly over the entire surface of the infected nail or nails. It is important to allow the lacquer to dry thoroughly, which typically takes around 10 minutes. The lacquer is resistant to soap and water, so individuals can continue their regular hand and foot hygiene routines without disrupting the treatment.
The duration of treatment with Loceryl depends on the severity and location of the infection. For fingernails, it typically takes up to six months to clear the infection, while toenails may require 9 to 12 months or longer. It is important to continue treatment without interruption until the nail is regenerated and the affected areas are fully cured.
As with any medication, it is essential to follow the instructions provided by your doctor or healthcare professional. Loceryl may cause side effects such as skin irritation, nail damage, and discolouration, and it should be avoided during pregnancy and breastfeeding unless specifically advised by a doctor.
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It is used to treat fungal infections of the nails
Loceryl nail lacquer is used to treat fungal infections of the nails. It contains the active ingredient amorolfine, an antifungal that kills a wide variety of fungi that cause nail infections. It also inhibits the enzymes that are essential for fungal growth.
To use Loceryl nail lacquer, the nail must first be prepared. The affected areas of the nail should be filed down as much as possible using a nail file. The surface of the nail should then be cleaned to remove any grease or surface germs. It is important to use a separate nail file and cleaning swab for each infected nail to prevent the spread of infection.
Once the nail has been prepared, the nail lacquer can be applied. The applicator should be dipped into the bottle of nail lacquer without wiping off the excess on the bottle neck. The lacquer should then be applied evenly over the entire surface of the infected nail or nails. It is important to allow the lacquer to dry for at least 10 minutes before applying any cosmetic nail varnish. Loceryl nail lacquer is resistant to soap and water, so you can wash your hands and feet as normal after application. However, if you need to use chemicals such as paint thinners or white spirit, you should wear impermeable gloves to protect the lacquer.
Treatment with Loceryl nail lacquer should be continued until the infection has cleared and healthy nails have grown back. This usually takes 6 months for fingernails and 9 to 12 months for toenails. It is important to follow the directions of your doctor regarding the frequency and duration of treatment, as this may vary depending on the type and severity of the infection.
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It contains amorolfine, an active ingredient that kills a wide variety of fungi
Loceryl nail gel is used to treat fungal infections of the nails. It contains amorolfine, an active ingredient that kills a wide variety of fungi. Amorolfine is a broad-spectrum antifungal agent that belongs to a new chemical class. Its fungicidal action is based on altering the fungal cell membrane, specifically targeting sterol biosynthesis. The reduction of ergosterol content and the accumulation of unusual sterically nonplanar sterols disrupt the fungal cell membrane, leading to the eradication of the fungi.
Amorolfine is present in the form of hydrochloride, and its chemical description is cis-4- [(RS)-3 [4-(1,1-Dimethylpropyl) phenyl]-2-methylpropyl]-2,6-dimethylmorpholine. It is highly effective against a range of fungi, including dermatophytes, yeasts, and moulds, which are common causes of nail infections. The nail lacquer containing amorolfine is applied directly to the affected nails, penetrating the nail plate and diffusing through to reach the nail bed. This unique ability to penetrate the nail allows it to target and kill fungi that are difficult to access by other means.
The application process for Loceryl nail gel involves several steps to ensure effective treatment. Firstly, it is essential to file down the affected areas of the nail thoroughly using the nail file provided in the kit. This step creates a rough and porous surface, enabling the lacquer to penetrate better. After filing, the nail surface should be cleaned and degreased using the provided cleaning pad or wipe to remove any remaining germs and grease. This step ensures that the lacquer can effectively target the infection and prevents the spread of the infection to other nails.
Once the nail is prepared, the Loceryl nail lacquer can be applied. The applicator is dipped into the bottle without wiping off the excess, and then it is applied evenly over the entire surface of the affected nail, including the underside. It is important to let the lacquer dry for at least 10 minutes before considering any additional steps. If desired, cosmetic nail varnish can be applied on top of the Loceryl lacquer after waiting for at least 10 minutes. However, it is crucial to remove any previous nail varnish or lacquer before reapplying Loceryl to ensure its effectiveness.
The frequency of application may vary depending on the severity and location of the infection. Generally, it is recommended to apply Loceryl nail gel once a week, but in some cases, twice-weekly applications may be beneficial. It is important to continue the treatment without interruption until the nail is regenerated and the infection is completely cleared, which can take up to 6 months for fingernails and 9 to 12 months for toenails. During this extended treatment period, it is advisable to maintain a regular application schedule and consult a doctor or pharmacist if there are any concerns about the effectiveness of the treatment.
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It is applied directly to the nail, killing the fungi and yeast
Loceryl Nail Lacquer is a prescription-only medication for treating fungal nail infections. It is applied directly to the nail, killing the fungi and yeast, and clearing the infection. The active ingredient in Loceryl is amorolfine, which is an antifungal medicine. Amorolfine belongs to a new chemical class, and its fungicidal action is based on altering the fungal cell membrane, specifically targeting sterol biosynthesis. The ergosterol content is reduced, and unusual sterically nonplanar sterols accumulate.
Before the first application of Loceryl, the infected nail should be filed down as much as possible using a nail file. The nail surface should then be cleaned with a wipe or swab to remove any grease or germs. It is important to note that the same nail file and nail varnish remover should not be used on healthy nails, as this may spread the infection.
Once the nail is prepared, the Loceryl lacquer can be applied using the same technique as applying nail polish. It should be applied evenly over the entire surface of the infected nail, including the underside, and allowed to dry for about 10 minutes. It is recommended to apply the lacquer once a week, although twice-weekly applications may be beneficial in some cases. It is important to continue treatment without interruption until the nail is regenerated and the infection is cured, which can take up to 6 months for fingernails and 9 to 12 months for toenails.
During treatment with Loceryl, it is advised to avoid the use of artificial nails and to remove any nail varnish before reapplying the lacquer. Additionally, Loceryl contains alcohol (ethanol), which is flammable, so caution should be exercised when using it near open flames or other sources of ignition.
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Treatment can take up to 12 months for toenails
Loceryl Nail Lacquer is a prescription-only treatment for fungal nail infections. It is applied directly to the nail, killing the fungi and yeast and clearing the infection. The lacquer is resistant to soaps and water and remains on the nails, allowing individuals to go about their daily lives without interruption.
Loceryl contains the active ingredient amorolfine (as the hydrochloride), which belongs to a group of medicines known as antifungals. Amorolfine is a broad-spectrum antimycotic that alters the fungal cell membrane, reducing ergosterol content and causing the accumulation of unusual sterically nonplanar sterols. It is highly active against a wide variety of fungi, with the exception of Actinomyces and Propionibacterium acnes, which is only slightly sensitive.
The length of treatment with Loceryl depends on the severity of the infection and the localisation of the affected nails. For toenails, treatment can take up to 9 to 12 months to be successful, whereas fingernails typically take around 6 months. Nails grow relatively slowly, and during treatment, individuals are waiting not only for the infected nail to grow out but also for new, healthy nails to grow in their place. It is recommended that individuals continue using Loceryl until the infection has cleared and healthy nails have grown back.
To use Loceryl, individuals should follow the steps outlined below:
- File the nail: Before the first application, file down the infected areas of the nail, including the nail surface, as much as possible using the nail file provided.
- Clean the nail: Use one of the swabs provided to clean the nail surface and remove any nail polish or grease.
- Apply the lacquer: Dip the applicator into the bottle of nail lacquer and apply the lacquer evenly over the entire surface of the nail and its underside. Allow the lacquer to dry for approximately 10 minutes.
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Frequently asked questions
Loceryl nail gel is used to treat fungal infections of the nails. It contains the active ingredient amorolfine, which is an antifungal medicine.
Loceryl nail gel works by penetrating the nail plate and diffusing through the nail to eradicate fungi in the nail bed. It also inhibits the enzymes essential for fungal growth.
First, file down the infected nail as much as possible using the nail file provided. Then, clean the nail surface with a swab or cleaning wipe. Dip the applicator into the bottle of nail lacquer and apply the gel evenly over the entire surface of the nail. Allow the gel to dry for at least 10 minutes.
Loceryl nail gel should be applied once or twice a week, as directed by your doctor. Treatment should be continued without interruption until the nail is regenerated and the infection is cured, which can take up to 6 months for fingernails and 9 to 12 months for toenails.
Some common side effects include blisters on the skin, nail damage and discolouration, skin irritation, rash, or redness at the site of application. Loceryl nail gel contains alcohol (ethanol), which may cause a burning sensation on damaged skin. It is flammable and should be kept away from open flames or lit cigarettes. Do not use if you are pregnant or breastfeeding.











































