
Inhaling nail polish remover is extremely dangerous and can cause serious harm to your health. It is a form of inhalant abuse, which involves inhaling common household products to get high. Inhalant use stimulates the brain's reinforcement and reward systems, leading to compulsive behaviour and dependence. The health risks of sniffing nail polish remover include cardiac arrest, suffocation, and Sudden Sniffing Death Syndrome. Over time, chronic solvent encephalopathy or painter syndrome can develop, causing walking problems, speech issues, and memory loss.
| Characteristics | Values |
|---|---|
| Reason for sniffing | To get intoxicated or experience a mind-altering event or "high" |
| Health risks | Cardiac arrest, suffocation, permanent damage to heart, lungs, kidney, and liver, walking problems, speech problems, memory loss, coma, and sudden cardiac death |
| Treatment | There is no specific treatment to reverse the effects of inhalant intoxication. Treatment involves treating the life-threatening event that occurs as a result of the overdose—for example, stopping the seizure or restarting the heart |
| Symptoms of dependence | Chemical odors on breath or clothes, paint or other stains on hands, fingers, or clothes, changes in behavior, significant decrease in appetite and weight loss, sudden change in friends and hobbies, rapid decline in school performance, change in hygiene and grooming habits |
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What You'll Learn

Inhalant use disorder
Inhalant abuse can have serious short-term and long-term effects on the body. The short-term effects of inhalant abuse can include cardiac arrest, suffocation, accidental injury, and even death. The 2012 National Institute of Drug Abuse report found that Sudden Sniffing Death Syndrome is the most common cause of death related to inhalant use. The risk of death is present every time an individual inhales an inhalant.
Long-term inhalant use can lead to a variety of physical and psychological complications. Physical health conditions can include tuberculosis, sexually transmitted infections, bronchitis, and major or mild neurocognitive disorders. Inhalant abuse can also cause inhalant-induced psychotic disorder, depression, and inhalant intoxication delirium.
Inhalant use shares characteristics with other substance use disorders as it intensely and directly stimulates the reinforcement and reward systems of the brain. This compulsive use of the drug can lead to dependence, causing negative consequences and long-term health effects. According to a 2020 survey, 2.4 million people in the US aged 12 and older had used an inhalant in the past year.
If you or someone you know is struggling with inhalant use disorder, it is important to seek help. SAMHSA's National Helpline is a free, confidential, 24/7 treatment referral and information service for individuals and families facing mental and/or substance use disorders.
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Short and long-term health effects
Inhalants are vaporous substances that are commonly inhaled to experience a mind-altering event or a "high". Nail polish remover is one such common household substance that is abused as an inhalant. Inhalant use disorder shares characteristics with other substance use disorders because it intensely stimulates the reinforcement and reward systems of the brain. This compulsive use of the drug can lead to dependence, which can have negative consequences and long-term health effects.
Short-term health effects
People who sniff nail polish remover can experience chemical odors on their breath or clothes, paint or other stains on their hands, fingers, or clothes, changes in behavior, a significant decrease in appetite and weight loss, a sudden change in friends and hobbies, a rapid decline in school performance, and changes in hygiene and grooming habits.
Long-term health effects
Over time, people who sniff nail polish remover can develop a condition known as "painter syndrome" or organic solvent syndrome, which causes walking problems, speech problems, and memory loss. Regular misuse can also lead to damage to the heart, lungs, kidneys, and liver.
Inhalant use can also lead to seizures, coma, and sudden cardiac death—even for first-time users. Breathing in inhalants from a bag placed over the head can cause death from suffocation or asphyxiation. Sudden Sniffing Death Syndrome is a risk for inhalant users every time they huff and is the most common cause of death related to inhalant use.
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Risk of cardiac arrest, seizures, coma, and death
Sniffing nail polish remover can lead to cardiac arrest, seizures, coma, and death. The fumes from nail polish remover contain acetone, a toxic chemical that can cause serious health problems. Acetone is a solvent that is used to remove nail polish, but it is also a depressant that can slow down the central nervous system, including the respiratory system. When acetone is inhaled, it can cause respiratory depression, which can lead to cardiac arrest, seizures, coma, and even death.
Acetone can also cause neurological problems such as dizziness, headaches, confusion, and seizures. Inhaling high doses of acetone can cause coma and death. Additionally, people who sniff nail polish remover can develop a tolerance to the effects of acetone, leading to a dangerous cycle of addiction. This means that they need to inhale more and more acetone to achieve the same high, increasing their risk of serious health problems or death.
The health risks of sniffing nail polish remover are severe and can be unpredictable, even with small amounts of acetone. It is important to seek help if you or someone you know is sniffing nail polish remover. There are resources available to help people overcome addiction and reduce their risk of potentially fatal health issues.
Furthermore, sniffing nail polish remover can also lead to asphyxiation, which is a lack of oxygen. Asphyxiation can occur if the person inhaling the fumes vomits or if they pass out and suffocate. This emphasizes the deadly nature of nail polish remover inhalation, as the risk of sudden death is always present.
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Painter syndrome
The condition primarily affects individuals who intentionally sniff nail polish remover to get high, as well as those working in poorly ventilated nail salons. The frequent inhalation of these toxic fumes can lead to serious neurological and physical impairments.
In addition to the direct health impacts, Painter syndrome can also have indirect effects on an individual's life. The walking and speech difficulties may require the use of assistive devices or therapies to improve mobility and communication. The memory loss component of Painter syndrome can lead to individuals requiring supervised care or assistance with daily tasks.
While the health effects of Painter syndrome are severe, it is important to note that they can be prevented. Raising awareness about the dangers of inhaling nail polish remover fumes and improving ventilation in nail salons can help reduce the risk of developing this syndrome. Additionally, the formulation of nail polishes has evolved, with some brands now offering "3-free" or "5-free" formulas that exclude certain toxic chemicals. However, it is important to recognize that even these formulas may still contain other toxic compounds. Proper disposal of nail polish and its classification as a household hazardous waste are also crucial steps in mitigating the health and environmental risks associated with its toxic chemicals.
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Prevalence among teenagers
Inhalant use disorder is a type of substance use disorder. People who use inhalants inhale common household products to get high. Nail polish remover is one such product that is commonly misused by teenagers.
Inhalant use disorder is more common among men than women, and children and teenagers aged 12 to 17 are the most common age group that uses inhalants. In 2020, they made up the largest percentage of inhalant users at 2.7%. However, studies have shown that children as young as 5 have used inhalants.
The reasons for this can be attributed to the accessibility of nail polish remover, as well as the misconception that it is harmless. Teenagers often use these substances because they are inexpensive and easy to find. They may also view it as a way to "'chill and relax", or as a way to cope with peer pressure.
The dangers of sniffing nail polish remover are often underestimated. The fumes are toxic and can be absorbed through the skin in large quantities, contaminating the air and causing a toxic buildup. The chemical acetone in nail polish remover is a potent solvent that can damage your health. It can interfere with hormones and organ functions and, in the worst cases, cause sudden cardiac death, even for first-time users.
It is important for parents and teachers to be aware of the signs of inhalant use disorder, such as changes in behaviour, academic performance, and friend circles. By having open dialogues with children about drug abuse, the risks of substance abuse can be mitigated.
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Frequently asked questions
Inhalants are vaporous substances that are commonly inhaled to experience a mind-altering event or "high".
Sniffing nail polish remover can lead to seizures, coma, and sudden cardiac death—even for first-time users.
Regular misuse of inhalants can lead to damage to the heart, lungs, kidney, and liver. It can also lead to dependence and negative consequences in other areas of life.
Signs include chemical odors on their breath or clothes, paint stains on their hands or clothes, changes in behavior, significant weight loss, and rapid decline in school performance.
If someone is experiencing nail polish remover poisoning, call the local emergency number (e.g. 911 in the US) or the local poison control center. Do not make the person throw up. Seek immediate emergency medical care.











































